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Genscript Corporation Antibody Protein Proteins Proteins 1 MG 1/EA
Supplier: Genscript Corporation Z037271
Fibroblast Growth Factor-basic (FGF-basic) also known as FGF-2 is a pleiotropic cytokine and one of the prototypic members of the heparin-binding FGF family. Like other FGF family members FGF-basic has theBeta trefoil structure. In vivo FGF-basic is produced by a variety of cells including cardiomyocytes fibroblasts and vascular cells. FGF-basic regulates a variety of processes including cell proliferation differentiation survival adhesion motility apoptosis limb formation and wound healing. FGF-basic can be tumorigenic due to its role in angiogenesis and blood vessel remodeling. The angiogenic effects of FGF-basic can produce beneficial cardioprotection during acute heart injury.
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