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AdipoGen anti-FGF-19 (human), mAb (FG369-1) (50 µg)
Supplier: AdipoGen AG20A0066C050
Monoclonal Antibody. Recognizes human FGF-19. Detects a band of ~25kDa by Western blot. Isotype: Mouse IgG1kappa. Clone: FG369-1. Applications: ELISA, IHC, WB. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. FGF-19 is involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. FGF-19 plays an important role in brain development during embryogenesis. FGF-19 binds only to FGF receptor 4 (FGFR4). Activity requires the presence of KLB.
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