Invitrogen™ Human FGFR2 [N549H], GST Tag Recombinant Protein

Catalog No.	Quantity
A33726	1 mg
A33503	10 μg
A33557	100 μg

Catalog No. A33726 Supplier Invitrogen™ Supplier No. A33726

Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. This FGFR2 N549H recombinant human protein (285-end) was expressed in insect cells. FGFR2 N549H recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service. Validated for use with the Z'-LYTE™ assay Available in multiple pack sizes for convenient use Also available in our SelectScreen Kinase Profiling Service Protein Form: Recombinant, Active, Cytoplasmic, Mutant The gene accession number for FGFR2 [N549H] is AAH39243.2.

FGFR2 receptor tyrosine kinase is a member of the fibroblast growth factor receptor family which plays a role in mitogenesis and differentiation. FGFR2 is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, and mutations in FGFR2 are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. FGFR2 is required for early postimplantation development between implantation and the formation of the egg cylinder. FGFR2 contributes to the outgrowth, differentiation, and maintenance of the inner cell mass.

Specifications

• Accession Number: P21802
• Concentration: See Label
• For Use With (Application): Kinase Assay
• Formulation: 50mM tris HCl with 25% glycerol, 0.25mM DTT, 0.1mM PMSF, 150mM NaCl, 10mM glutathione, 0.1mM EDTA and no preservative; pH 7.5
• Gene ID (Entrez): 2263
• Molecular Weight (g/mol): 74 kDa
• Name: Human FGFR2 [N549H], GST Tag
• pH Range: 7.5
• Purification Method: Purified
• Quantity: 1 mg
• Storage Requirements: -80°C, Avoid Freeze/Thaw Cycles
• Regulatory Status: RUO
• Gene Alias: FGFR2
• Common Name: FGFR2 (N549H Mutant)
• Gene Symbol: FGFR2
• Kinase Family: FGF Receptors
• Protein Length: 285-end
• Product Type: Protein
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: GST-tag
• Sequence: 285-end
• Content And Storage: -80°C, Avoid Freeze/Thaw Cycles
• Shipping Condition: Dry Ice
• Expression System: Insect cells
• Protein Family: Growth Factors & Receptors
• Protein Form: Recombinant, Active, Cytoplasmic, Mutant
• Form: Liquid