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Apexbio Technology LLC FH1(BRD-K4477) 2719-05-3 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC B37005.1
FH1 BRD-K4477 is a bioactive small molecule identified for its ability to enhance hepatocyte functionality FH1 BRD-K4477 promotes the expansion and functional maturation of cultured human hepatocytes maintaining liver-specific properties In studies involving induced pluripotent stem cell (iPSC)-derived hepatocytes (iHeps) FH1 BRD-K4477 supplementation increases albumin secretion and elevates the expression of drug-metabolizing enzyme CYP3A4 while reducing alpha-fetoprotein (AFP) secretion Based on these pharmacological properties FH1 BRD-K4477 is a valuable tool for research in liver biology hepatocyte maturation drug metabolism and regenerative medicine applications
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