fibronectin is purified from human plasma (Cat. No. f0895). The protein is modified to contain covalently linked fluorescein 5-isothiocyanate (Cat. No. f7250).fibronectin also known as Cold-insoluble globulin is a large glycoprotein of the extracellular matrix that is coded by fN1 gene. It is expressed in the plasma and at the cell surface. fibronectin is a ubiquitous and essential component of the extracellular matrix (ECM) and plays a vital role during tissue repair. fibronectin functions both as a regulator of cellular processes and an important scaffolding protein to maintain and direct tissue organization and ECM composition. fibronectin plays an important role in cell adhesion and spreading and affect the routes of cell migration both in vivo and in culture. Proteolytic degradation of extracellular matrix (ECM) is a critical step during cell invasion and tissue transmigration that is required for many physiological and pathological processes. Cellular structures that mediate ce