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Sigma Aldrich Fine Chemicals Biosciences fibronectin human plasma l5MG
Supplier: Sigma Aldrich Fine Chemicals Biosciences F20065X5MG
fibronectin (fN) is a multifunctional glycoprotein the gene of which is localized to human chromosome 2q34-36. This gene spans 75kb and contains 50 exons. It exists as two major isoforms one soluble and one insoluble form. The former is present in plasma whereas the insoluble form resides in tissues and extracellular matrix (ECM) of cartilage. There are around 20 different forms of fN due to alternative splicing of a variable region and two type III exons called Extra Domains A and B.
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