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Cayman Chemical FInasterIde 50mg
Supplier: Cayman Chemical 1493850 MG
An inhibitor of 5α-reductase type II (IC50 = 4.2 nM); 100-fold selective for 5α-reductase type II over type I; does not affect the growth of androgen-refractory PC3 prostate cancer cells but increases the protein levels of Nrf2 and HO-1; decreases prostatic diameter and volume, as well as dihydrotestosterone serum levels in dogs with spontaneous benign prostatic hypertrophy at 0.1 and 0.5 mg/kg; reduces testosterone-induced type I procollagen and TGF-β1 protein levels in cultured human scalp dermal fibroblasts in a model of androgenic alopecia at 0.1 µM
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