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Medchemexpress LLC Firazorexton hydrate (TAK-994) | 2861934-86-1 | 99.9% | 497.53 | 1 MG
SDP

Catalog No. 5000350229
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Firazorexton hydrate (TAK-994) is an orally active and brain-penetrant orexin type 2 receptor (OX2R) selective agonist. It promotes wakefulness and has the potential to improve narcolepsy-like symptoms.

  • Orally active and brain-penetrant orexin type 2 receptor (OX2R) selective agonist
  • Promotes wakefulness
  • Improves narcolepsy-like symptoms in mice models
  • Increases calcium mobilization in hOX2R/CHO-K1 cells with an EC50 of 19 nM
  • Activates downstream signals of OX2R
  • Increases total wakefulness time in C57BL/6J mice
  • Ameliorates fragmentation of wakefulness

Catalog No. 50-003-50229 Supplier Medchemexpress LLC Supplier No. HY137440A1MG
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Firazorexton hydrate (TAK-994) is an orally active and brain-penetrant orexin type 2 receptor (OX2R) selective agonist. It promotes wakefulness and has the potential to improve narcolepsy-like symptoms.

  • Orally active and brain-penetrant orexin type 2 receptor (OX2R) selective agonist
  • Promotes wakefulness
  • Improves narcolepsy-like symptoms in mice models
  • Increases calcium mobilization in hOX2R/CHO-K1 cells with an EC50 of 19 nM
  • Activates downstream signals of OX2R
  • Increases total wakefulness time in C57BL/6J mice
  • Ameliorates fragmentation of wakefulness

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