FITC-Dextran MW 70000 (CAS 60842-46-8) is a fluorescent-labeled polysaccharide probe synthesized by conjugating fluorescein isothiocyanate (FITC) to dextran It is designed to enable visualization and quantitative analysis of permeability endocytic uptake and transport phenomena in biological systems FITC-Dextran MW 70000 exhibits its utility by emitting fluorescence upon excitation (Ex 495 nm Em 519 nm) allowing detection via fluorescence microscopy flow cytometry or spectrofluorometry In experimental models it is commonly used for evaluating epithelial barrier integrity in intestinal vascular and blood-brain barrier assays and for investigating uptake mechanisms in cellular biology Based on these properties FITC-Dextran MW 70000 is valuable for research applications in membrane permeability trans-barrier transport studies endocytosis assays and cellular uptake investigations