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Selleck Chemical LLCSupplier Diversity Partner Tacrolimus (FK506) 50mg 104987-11-3 FR900506, Fujimycin, Prograf  DFS Item

Manufacturer:  Selleck Chemical LLCSupplier Diversity Partner S500350MG

Tacrolimus (FK506, FR900506, Fujimycin, Prograf) is a 23-membered macrolide lactone, it reduces peptidyl-prolyl isomerase activity in T cells by binding to the immunophilin FKBP12 (FK506 binding protein) creating a new complex. Tacrolimus also inhibits the phosphatase activity of calcineurin. Tacrolimus induces vascular endothelial autophagy.

Catalog No. 50-648-3


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