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Enzo Life Sciences FK506, (5mg), CAS Number: 104987-11-3

Supplier: Enzo Life Sciences ALX380008M005

Immunosuppressant. Immunosuppressant that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2. Shown to inhibit the activity of FK506 binding protein and to inhibit the Ca2+-dependent phosphatase and protein phosphatase 2B (PP2B; calcineurin). Activates NF-κB through phosphorylation and degradation of IκBα. Alternative Name: Tacrolimus. Formula: C44H69NO12. MW: 804.0. CAS Number: 104987-11-3. MI: 14: 9025. Purity: ≥98% (HPLC). Appearance: White to off-white crystalline powder. Solubility: Soluble in DMSO, 100% ethanol, methanol, ethyl acetate or acetone; insoluble in water. Long Term Storage: -20°C
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