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Medchemexpress LLC FKBP12 PROTAC RC32 | 2375555-66-9 | 97.0% | 100 MG
Supplier: Medchemexpress LLC HY130835100MG
FKBP12 PROTAC RC32 (RC32) is a potent FKBP12 degrader that utilizes PROTAC technology. It is a conjugate of Rapamycin and a ligand for a Cereblon E3 ubiquitin ligase, designed to efficiently degrade FKBP12 protein.
- Potent degrader of FKBP12
- Based on PROTAC technology
- Contains conjugation of Rapamycin and a ligand for a Cereblon E3 ubiquitin ligase
- Efficiently degrades FKBP12 protein in most organs (in vivo studies)
- Induces FKBP12 protein degradation in human Jurkat cells (DC50 ~0.3 nM)
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