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Cayman Chemical FlavokawaIn C 10mg
Supplier: Cayman Chemical 3939310 MG
A chalcone with enzyme inhibitory and anticancer activities; inhibits collagenase and elastase in cell-free assays (IC50s = 62.05 and 17.6 µM, respectively); cytotoxic to HCT116, HT-29, MCF-7, A549, and Ca Ski cancer cells (IC50s = 12.75, 39, 47.63, 40.28, and 39.88 µM, respectively); induces apoptosis and cell cycle arrest at the G1 phase in HCT116 cells at 20, 40, and 60 µM; reduces tumor volume and induces intratumoral necrosis and apoptosis in an HCT116 mouse xenograft model at 1 and 3 mg/kg
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