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Selleck Chemical LLC Flavopiridol (Alvocidib) 100mg 146426-40-6 NSC 649890 HCl,HMR-1275
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Supplier:  Selleck Chemical LLC S1230100MG

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Flavopiridol (Alvocidib, NSC 649890, HMR-1275) competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4, CDK6, and CDK9 with IC50 values in the 20-100 nM range. It is more selective for CDK1, 2, 4, 6, 9 versus CDK7. Flavopiridol is initially found to inhibit EGFR and PKA. Flavopiridol induces autophagy and ER stress. Flavopiridol blocks HIV-1 replication. Phase 1/2. *For Research & Development use only.  Product is not intended for drug, household, or human consumption.

Catalog No. 50-830-4


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