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Apexbio Technology LLC Flecainide acetate 54143-56-5 10mg
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Supplier:  Apexbio Technology LLC A341810

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Flecainide acetate (CAS 54143-56-5) is a nonselective sodium channel blocker classified as a class 1C antiarrhythmic agent It primarily inhibits the cardiac Nav1 5 sodium channel resulting in action potential prolongation and suppression of sodium current-dependent calcium signaling in cardiomyocytes Flecainide has been shown to reduce calcium spark and wave frequency modulate refractoriness and extend effective refractory periods (ERP) particularly affecting repolarization across ventricular walls In experimental rat models flecainide demonstrates dose-dependent reductions in heart rate and blood pressure increases QRS interval and influences Ca(2 ) efflux via the Na( )/Ca(2 )-exchanger This compound is widely utilized in studies of arrhythmia mechanisms electrophysiology and cardiac excitation-contraction coupling

Catalog No. 50-000-94072


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