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Cayman Chemical Flndersa maculosa Coln 5mg

Supplier: Cayman Chemical 299465 MG

A synthetic polypeptide and CCK2 receptor agonist binds selectively to CCK2 in guinea pig brain over CCK1 receptors in rat pancreas (IC50s 11 and 1100 nM respectively) increases calcium influx and polyphosphoinositide turnover in rat GH3 pituitary cells (EC50s 23 and 3 9 nM respectively) increases histidine decarboxylase activity in mucous and endocrine cell-enriched isolated rabbit fundic mucosal cells (EC50 2 9 nM) induces contraction of isolated pig ileum smooth muscle cells in vitro (EC50 30 pM) increases gastric acid and pepsin secretion in conscious cats in vivo (ED50s 1 29 and 57 3 nmol/kg2 per hour respectively)
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