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Cayman Chemical FludarabIn Phosphate 50mg

Supplier: Cayman Chemical 1425150 MG
A prodrug form of fludarabine and 2-fluoro-ara-ATP; reduces viability of, and induces apoptosis in, N-Myc-overexpressing LASCPC-01 cells (IC50 = 17.67 µM); reduces N-Myc protein levels when used at 25 µM for at least 48 hours; reduces tumor volume in N-Myc-overexpressing 22Rv1-N-Myc and LASCPC-01, but not non-N-Myc-overexpressing 22Rv1, mouse xenograft models at 120 mg/kg; an inhibitor of SARS-CoV-2 RdRp (EC50 = 0.93 µM)
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