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Cayman Chemical FludIoxonIl 50mg
SDP

Supplier:  Cayman Chemical 2581850 MG

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A glucosylceramide synthase inhibitor (IC50 40 nM for inhibition of glucosylceramide production in K562 cells) selective for glucosylceramide synthase over a-glucosidase I and II a-16-glucosidase lysosomal glucocerebrosidase non-lysosomal glucosylceramidase sucrase and maltase (IC50s 10 UM for all) decreases GM1 and GM3 cell surface levels in K562 and B16/F10 cells (IC50s 24 and 29 nM respectively) decreases glucosylceramide levels in the liver and lungs of D409V/null mice

Catalog No. 50-293-4353


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