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Cayman Chemical Flufenamic Acid, Purity: ≥98%, CAS: 530-78-9, 100 g
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Catalog No. 502994034
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An NSAID and COX inhibitor (IC50s = 3 and 9.3 µM for human COX-1 and COX-2, respectively); inhibits TNF-α-induced increases in COX-2 levels and NF-κB activation in HT-29 colon cancer cells in a concentration-dependent manner; inhibits fMLP- or A23187-induced calcium influx in PMN (IC50s = 29 and 14 µM, respectively); activates various ion channels, including TRPC6 and KCa1.1; inhibits various ion channels, including TRPC3 and CFTR; reduces increases in intestinal fluid secretion and intestinal barrier disruption in mice infected with the El Tor variant of V. cholerae at 20 mg/kg

Catalog No. 50-299-4034 Supplier Cayman Chemical Supplier No. 21447100 G
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An NSAID and COX inhibitor (IC50s = 3 and 9.3 µM for human COX-1 and COX-2, respectively); inhibits TNF-α-induced increases in COX-2 levels and NF-κB activation in HT-29 colon cancer cells in a concentration-dependent manner; inhibits fMLP- or A23187-induced calcium influx in PMN (IC50s = 29 and 14 µM, respectively); activates various ion channels, including TRPC6 and KCa1.1; inhibits various ion channels, including TRPC3 and CFTR; reduces increases in intestinal fluid secretion and intestinal barrier disruption in mice infected with the El Tor variant of V. cholerae at 20 mg/kg

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