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Medchemexpress LLC Fluocinolone (acetonide) | 67-73-2 | 99.7% | 1 G
Supplier: Medchemexpress LLC HYB04151G
Fluocinolone is a glucocorticoid receptor agonist. It is effective in preventing lipid accumulation and inflammation. Fluocinolone can promote the proliferation of DPCs and may help repair injured pulp tissues. It can also be used to study the prevention of chemotherapy-induced peripheral neuropathy caused by Paclitaxel.
- Improves foam cell survival in THP-1 cells.
- Inhibits inflammatory cytokines secretion and reduces cholesteryl ester accumulation.
- Promotes the proliferation of DPCs.
- Promotes the expressions of BSP, OCN, DSPP, and Wnt4, and up-regulates Wnt4 and the dentin-specific marker dentin sialophosphoprotein.
- Prevents development of significant peripheral neuropathy in a mouse model of PTX-induced.
- Prevented a marked reduction in intraepidermal nerve fibers density in the plantar surface of the hind paws in a PTX-induced peripheral neuropathy model.
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