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Fluorescein-CREBtide Substrate

Supplier: LIFE TECHNOLOGIES PV3508

Catalog No. PV3508

$1,192.00 / Each of 1

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Description

A fluorescein-labeled peptide substrate that is based upon the CREB ( cAMP responsive element binding) protein. The peptide substrate is phosphorylated by a wide range of Ser/Thr kinases.

For use in combination with the LanthaScreen™ Tb-CREB [pSer133] antibody (PV3542) to evaluate inhibitors in medium to high throughput screening applications.

Specifications

Amino Acid Sequence	Fluorescein- KRREILSRRPSYR
Content And Storage	1 mg/mL Fluorescein-CREBtide substrate in water. Store at -20°C and protect from light.
Quantity	1 mg
Substrate Properties	Peptide-Based Substrate
Target Enzyme	Serine/Threonine Kinases
Molecular Weight (g/mol)	2076 Da
Target Entry	AMPK (A2/B1/G1), STK22D, CAMK2B, CHEK1, MAPKAPK2, PASK, PIM2, PRKCN, PRKD2, PRKG2, RPS6KA5, AMPK (A1/B1/G1), AURKA, CAMK1D, CAMK4, CHEK2, MAPKAPK3, PIM1, PKN1, PRKD1, PRKG1, RPS6KA4, CAMK1

Assay Entry	Biochemical terbium phospho-specific activity
Detection Method	Fluorescence
Substrate	Fluorescein-CREBtide
Substrate Type	Kinase Substrate
Label or Dye	FITC (Fluorescein)
Shipping Condition	Dry Ice
Validated Kinases	AMPK, AURKA, CAMK1, CAMKID, CAMK2A, CAMK2B, CAMK4, CHEK1, CHEK2, MAPKAPK2, MAPKAPK3, PASK, PIM1, PIM2, PKN1, PRKACA, PRKD1, PRKD2, PRKG1, PRKG2, RPS6KA4, RPS6KA5, STK22D

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Fluorescein-CREBtide Substrate

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