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Apexbio Technology LLC Fluoroorotic Acid, Ultra Pure 703-95-7 5g
Supplier: Apexbio Technology LLC A25315000
Fluoroorotic Acid Ultra Pure (CAS 703-95-7) is a small-molecule antimetabolite targeting orotidine-5 -phosphate decarboxylase It is designed to interfere with pyrimidine biosynthesis thereby enabling selective pressure in genetic experiments Fluoroorotic Acid Ultra Pure exerts its biological activity primarily through intracellular conversion to the toxic intermediate 5-fluorouracil mediated by orotidine-5 -phosphate decarboxylase In yeast-based studies particularly involving Saccharomyces cerevisiae it demonstrates selective inhibition with an IC50 value of approximately 0 1 1 mM in wild-type yeast strains Based on these pharmacological properties Fluoroorotic Acid Ultra Pure holds research potential in genetic selection recombinant strain construction and functional gene analysis in microbial genetics
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