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Apexbio Technology LLC Fluoxetine HCl(Synonyms: Prozac, Sarafem, Fluoxetine Hydrochloride, Lilly 110140, Fluoxeren, Fluctin), 10mM (in 1mL DMSO), CAS: 56296-78-7.
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Supplier:  Apexbio Technology LLC A24365.1

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Fluoxetine HCl (CAS 56296-78-7) is a selective serotonin reuptake inhibitor (SSRI) that specifically blocks presynaptic serotonin (5-HT) transporters resulting in elevated extracellular serotonin levels It modulates serotonergic signaling through inhibition of serotonin-induced membrane currents in cloned 5HT2C receptors exhibiting an IC50 around 20 M and binds 5HT2C receptors expressed in HeLa cells (Ki approximately 65-97 nM) Fluoxetine treatment has been shown in vivo to stimulate neurogenesis and enhance neuronal maturation and synaptic plasticity within rat hippocampus and prefrontal cortex Widely employed in neuroscience research fluoxetine aids in studies of depression stress resilience and neuro-regulatory mechanisms involving serotonergic signaling

Catalog No. 50-000-60266


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