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Cayman Chemical FlupIrtInmaleate 50mg
Supplier: Cayman Chemical 1667450 MG
An activator of Kv7/KCNQ; induces relaxation of preconstricted pulmonary arteries isolated from wild type and SERT+ mice; decreases mean right ventricular pressure and right ventricular hypertrophy in hypoxia-induced and SERT+ mouse models of pulmonary arterial hypertension at 30 mg/kg per day; increases the paw withdrawal threshold in a rat model of streptozotocin-induced diabetic neuropathy at 10 mg/kg; increases paw withdrawal latency in a rat model of carrageenan-induced paw inflammation when used in combination with morphine; indirectly antagonizes NMDA receptors via its effects on potassium channels
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