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Cayman Chemical Fluprostenol ELISA Stndard 1ea
SDP

Supplier:  Cayman Chemical 4167641 EA

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An inhibitor of EGFRL858RT790M (IC50 1.1 nM) selective for EGFRL858RT790M over BTK wild-type EGFR FAK HER2 and HER4 (IC50s 213 226 255 392 and 704 nM respectively) but also inhibits wild-type EGFR containing an exon 19 deletion EGFRT790M containing an exon 19 deletion EGFRL585R EGFRG192A and EGFRL861Q (IC50s 1.3-12 nM) reduces tumor volume in a PDX mouse model of NSCLC at 25 and 50 mg/kg twice per day

Catalog No. 50-294-3340


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