Cayman Chemical FlutIcason Furoate 10mg

Supplier:  Cayman Chemical 2987810 MG

A synthetic glucocorticoid; selective for the glucocorticoid receptor over the mineralocorticoid, progesterone, and androgen receptors in reporter assays (EC50s = 0.03, 23.4, 0.9, and >10,000 nM, respectively), as well as ERα and ERβ in scintillation proximity assays (EC50s = >10,000 nM); reduces LPS-induced increases in TNF-α production in human PBMCs (EC50 = 0.12 nM); decreases S. aureus enterotoxin-induced increases in IFN-γ, IL-2, IL-5, IL-17, and TNF-α levels in patient-derived nasal polyp tissue in vitro at 100 nM; reduces ovalbumin-induced increases in BALF eosinophil infiltration in a rat model of allergic inflammation at 30 UG/animal intrathecally

Catalog No. 50-299-1209