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Medchemexpress LLC Fluticasone propionate | 80474-14-2 | 99.93% | 200 MG
Supplier: Medchemexpress LLC HYB0154200MG
Fluticasone propionate is a potent topical anti-inflammatory corticosteroid and a selective glucocorticoid receptor agonist with an absolute affinity (KD) of 0.5 nM. It exhibits little to no activity at other steroid receptors and also possesses anti-viral activity. Its applications span immunology, anti-infection, and metabolic research.
- Potent topical anti-inflammatory corticosteroid
- Selective glucocorticoid receptor agonist (KD of 0.5 nM)
- Exhibits minimal activity at other steroid receptors
- Possesses anti-viral activity
- Inhibits TNFα-induced E-selectin expression with an IC50 of 1 nM
- Targets glucocorticoid receptor, endogenous metabolite, enterovirus, and ADC payload
- Relevant to immunology/inflammation, vitamin D related/nuclear receptor, metabolic enzyme/protease, anti-infection, and antibody-drug conjugate/ADC related pathways
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