Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000247346

Medchemexpress LLC FM-381 | 2226521-65-7 | 99.6% | 428.49 g·mol^-1 | C24H24N6O2 | 5 MG
SDP

Supplier:  Medchemexpress LLC HY1020465MG

Encompass_Preferred

A potent covalent reversible inhibitor of Janus kinase 3 (JAK3) that targets the unique Cys909 residue. It displays subnanomolar biochemical potency and high selectivity, and is supplied as a solid for laboratory research applications.

  • IC50 of 127 pM for JAK3.
  • High selectivity: ~410x vs JAK1, ~2,700x vs JAK2, ~3,600x vs TYK2.
  • Purity 99.58% by analysis.
  • Molecular formula C24H24N6O2; molecular weight 428.49 g·mol^-1.
  • Solubility 8.33 mg/mL (≈19.44 mM) in DMSO.
  • Appearance: solid, light yellow to yellow.
  • Storage: powder -20°C for long term; in solvent -80°C recommended.
  • For research use only.

Catalog No. 50-002-47346


May include imposed supplier surcharges.
Add to Cart

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.