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ACROBiosystems FMC63 scFv, His Tag (CD9-M52Hb) is expressed from human 293 cells (HEK293). It mimics the scFv presented on CAR-T cells which target CD19.

Supplier:  ACROBiosystems CD9M52HB100UG

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FMC63 is an IgG2a mouse monoclonal antibody specific for CD19, which is a target for the immunotherapy of B lineage leukaemias and lymphomas. FMC63 scFv is the most commonly used ectodomain component of CD19-specific CARs. So far, most of reported CART19 trials contain the anti-CD19 scFv derived from FMC63, including the two FDA-approved CARs Kymriah and Yescarta.

Catalog No. 50-225-4079


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