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  6. Sigma Aldrich Fmoc-™-2-(7-Octenyl)Ala-Oh 

Sigma Aldrich Fmoc-™-2-(7-Octenyl)Ala-Oh

Catalog No. F65621G Shop All MilliporeSigma Sigma Organic Chemistry Products
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F65621G 100 g
F65625G 1 g
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Description

MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.

Olefinic alpha-methyl amino acid for peptide stapling. Upon incorporation of this amino acid into a peptide, along with another of the same or derivative with a different length of the olefinic side chain, the two can be 'stapled' via a ring closing metathesis reaction with Grubb's catalyst (product # 579726). The resulting stapled peptide macrocycle has been shown to stabilize the alpha-helical structure of peptides, which can lead to favorable biological characteristics such as increased proteolytic stability and cellular uptake.

Specifications

CAS 59-30-3
Melting Point > 285°C
Molecular Formula C19H19N7O6
Linear Formula C19H19N7O6
MDL Number MFCD00079305
Quantity 100 g
Molecular Weight (g/mol) 441.4 g/mol
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