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Bachem Fmoc-Asp(2-phenylisopropyl ester)-OH
SDP

Supplier:  Bachem 4019087.0001

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Fmoc-Asp(2-phenylisopropyl ester)-OH, 200336-86-3, C28H27NO6, Mr 473.53, 1g. Fmoc-Asp(OPp)-OH, Fmoc-Asp(O-2-PhiPr)-OH. An aspartic acid derivative allowing specific side chain deprotection with 1% TFA in dichloromethane. Ocampo et al. applied OPp protection during the synthesis of a peptide-oligonucleotide conjugate and cleaved it with 3% trichloroacetic acid in DCM. The OPp derivative is far less prone towards base-catalyzed aspartimide formation than the OAll, OBzl, or ODmab esters, its stability comes close to the stability of the OtBu ester.

Catalog No. 50-258-654


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