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Bachem Fmoc-Asp(ODmab)-OH

Supplier: Bachem 4028316.0001

Fmoc-Asp(ODmab)-OH, 269066-08-2, C39H42N2O8, Mr 666.77, 1g. Dmab can be removed with 2% hydrazine in DMF generating an indazole which allows the UV-spectrophotometrical monitoring of the cleavage. Conroy et al. used this Asp derivative for the solid-phase synthesis of N-linked glycopeptides. As Dmab represents an unhindered p-substituted Z-derivative, Asp(Dmab)-containing peptides are prone to base-catalyzed aspartimide formation.
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