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Sigma Aldrich Fmoc-L-Photo-Methionine

Catalog No. 907367100MG Shop All MilliporeSigma Sigma Organic Chemistry Products
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90-736-7100MG 1 g
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MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.

Fmoc-L-photo-methionine is a diazirine-containing, Fmoc-protected methionine amino acid and multifunctional photo-crosslinker. Its incorporation into peptides or small-molecule probes and tools allows for photoaffinity labeling of cellular targets and protein-protein interactions upon UV light (≥360 nm) irradiation to form a covalent bond. This and other multifunctional probe building blocks will continue to accelerate drug discovery research for probing cellular mechanisms, target ID/validation, and understanding traditionally undruggable targets. An unprotected version is also available as 907375.Developing diazirine-based chemical probes to identify histone modification 'readers' and 'erasers 'Proteome profiling reveals potential cellular targets of staurosporine using a clickable cell-permeable probeCovalent Capture of Phospho-Dependent Protein Oligomerization by Site-Specific Incorporation of a Diazirine Photo-Cross-LinkerFishing for Drug Targets: A Focus on Diazirine Photoaffinity Probe SynthesisPhoto-affinity labeling (PAL) in chemical proteomics: a handy tool to investigate protein-protein interactions (PPIs)

Specifications

Melting Point >300°C
Molecular Formula C32H62P2Cl2Pd
Linear Formula C32H62P2Cl2Pd
Quantity 1 g
Synonym Umicore CX82
Molecular Weight (g/mol) 686.11 g/mol
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