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Bachem Fmoc-Pra-OH

Supplier: Bachem 4053914.0005
Fmoc-Pra-OH, 198561-07-8, C20H17NO4, Mr 335.36, 5g. Fmoc-Propargyl-Gly-OH, (S)-2-(Fmoc-amino)-4-pentynoic acid. Building block for the synthesis of precursor peptides for tritiation, and for "click chemistry". Pra-containing peptides have been modified by 1,3-dipolar cycloaddition, e.g. with alkyl azides. Peptides containing a Pra residue and an a-azido acid have been cyclized in the presence of CuBr/Na-ascorbate via triazole formation. Educt for the synthesis of Phe-derivatives by rhodium-catalyzed [2+2+2] cycloaddition.
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