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Medchemexpress LLC Fmoc-Val-Ala-PAB-OH | 1394238-91-5 | MFCD28557282 | 99.9% | 515.60 g/mol | C30H33N3O5 | 250 MG
Supplier: Medchemexpress LLC HY126353250MG
Fmoc-Val-Ala-PAB-OH is a protease-cleavable linker used in the synthesis of antibody-drug conjugates. It combines an Fmoc-protected Val-Ala dipeptide with a para-aminobenzyl spacer and a free carboxyl group to enable coupling and self-immolative payload release. Supplied as a high-purity solid, it includes documented solubility and storage guidelines for research use.
- Protease-cleavable Val-Ala dipeptide enables selective payload release.
- Fmoc protection facilitates solid-phase peptide and conjugation chemistry.
- Para-aminobenzyl spacer provides self-immolative release upon cleavage.
- High purity (99.88%) and characterized molecular weight for reliable synthesis.
- Soluble in DMSO with reported in vitro and in vivo formulation protocols.
- Supplied as a solid in small-scale packages suitable for research.
- Recommended storage at -20°C under inert atmosphere for stability.
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