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Cayman Chemical Folitixorin, Purity: ≥75% (mixture of diastereomers), CAS: 3432-99-3, 5 mg
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Catalog No. 502948768
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A reduced form of folate and cofactor for thymidylate synthetase; forms a ternary complex with thymidylate synthetase and FdUMP that inhibits thymidylate synthetase activity and DNA synthesis; has synergistic or additive cytotoxic effects against LS 174 or HT-29 human colon cancer cells, respectively, when used in combination with 5-fluorouracil; increases survival and reduces tumor growth in an HT-29 mouse xenograft model at 0.6 mg/animal when administered in combination with 5-fluorouracil

Catalog No. 50-294-8768 Supplier Cayman Chemical Supplier No. 339675 MG
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A reduced form of folate and cofactor for thymidylate synthetase; forms a ternary complex with thymidylate synthetase and FdUMP that inhibits thymidylate synthetase activity and DNA synthesis; has synergistic or additive cytotoxic effects against LS 174 or HT-29 human colon cancer cells, respectively, when used in combination with 5-fluorouracil; increases survival and reduces tumor growth in an HT-29 mouse xenograft model at 0.6 mg/animal when administered in combination with 5-fluorouracil

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