Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000063595

Apexbio Technology LLC Foretinib (GSK1363089) 849217-64-7 10mM (in 1mL DMSO)
SDP

Supplier:  Apexbio Technology LLC A29745.1

Encompass_Preferred

Foretinib (GSK1363089 CAS 849217-64-7) is a small molecule inhibitor targeting receptor tyrosine kinases involved in angiogenesis and tumor progression notably receptors for vascular endothelial growth factor (VEGF) and hepatocyte growth factor (HGF) Foretinib inhibits tyrosine kinase activity of Met Ron KDR Flt-1 Flt-4 KIT Flt-3 Tie-2 and PDGFR / exhibiting IC50 values ranging from 0 4 to 9 6 nmol/L In cell-based assays foretinib reduces MET phosphorylation in mouse B16F10 melanoma and human PC-3 prostate cells (IC50 21 23 nmol/L) inhibits HGF-induced cell migration invasion and suppresses proliferation in B16F10 A549 and HT29 tumor cell lines Foretinib is utilized in preclinical cancer research targeting angiogenesis invasion and metastasis pathways

Catalog No. 50-000-63595


May include imposed supplier surcharges.
Only null left
Add to Cart

Product Content Correction

The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.