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Cayman Chemical ForsythosIde B 50mg

Supplier: Cayman Chemical 2905150 MG

A selective Nav1 1 and Nav1 3 channel blocker (IC50s 10000 nM for Nav1 1 Nav1 3 Nav1 4 and Nav1 5-1 8 respectively) induces a concentration-dependent hyperpolarizing shift in voltage dependence of inactivation of Nav1 3 channels at 1 M substitution of the Nav1 3 VSD4 with the Nav1 5 VSD4 reduces potency by 500-fold
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