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Medchemexpress LLC Fosbretabulin disodium | 168555-66-6 | 99.9% | 440.29 | 5 MG
Supplier: Medchemexpress LLC HY174495MG
Fosbretabulin disodium (CA 4DP) is a tubulin destabilizing agent. It functions as a Combretastatin A4 proagent, selectively targeting endothelial cells. This action induces regression of nascent tumor neovessels, reduces tumor blood flow, and causes central tumor necrosis. It has demonstrated efficacy in inhibiting the growth of various cancer cell lines in vitro and reducing tumor blood flow in animal models.
- Acts as a tubulin destabilizing agent.
- Selectively targets endothelial cells.
- Induces regression of nascent tumor neovessels.
- Reduces tumor blood flow.
- Causes central tumor necrosis.
- Inhibits growth of multiple cancer cell lines.
- Decreases tumor blood flow in animal models.
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