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Medchemexpress LLC Foscarnet trisodium hexahydrate | 34156-56-4 | 99.5% | 300.04 | 5 G
Supplier: Medchemexpress LLC HYW0132565G
Foscarnet trisodium hexahydrate is a viral DNA polymerase activity inhibitor that reversibly suppresses viral replication. It is an antiherpesvirus agent used in cytomegalovirus retinitis.
- Viral DNA polymerase activity inhibitor.
- Leads to reversible suppression of viral replication.
- Antiherpesvirus agent.
- Used in cytomegalovirus retinitis.
- Inhibits human cytomegalovirus DNA polymerase (UL54) by mimicking the pyrophosphate leaving group of the nucleotide transfer reaction.
- Inhibits influenza A Victoria (IC50=29 μM), influenza B HK (IC50=61 μM), and avian myeloblastosis virus (IC50=5-8 μM), HSV-1, several strains (IC50=0.4-3.5 μM).
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