Medchemexpress LLC FOSL1 degrader 1 | 99.5% | 1124.19 g/mol | C58H69N5O18 | 10 MG

Supplier:  Medchemexpress LLC HY16272310MG

FOSL1 degrader 1 is a T-5224-based PROTAC designed to selectively degrade FOSL1 (AP-1), suppress cancer-stemness gene expression, and inhibit tumor growth in preclinical head and neck squamous cell carcinoma (HNSCC) models. It shows substantially increased potency compared with the parent inhibitor and is supplied as a solid with high purity for research use.

• Targets FOSL1 (AP-1) for proteasomal degradation
• Suppresses cancer stemness gene expression in HNSCC models
• Eliminates cancer stem cells and inhibits tumor growth in preclinical studies
• Demonstrates approximately 30-100x increased potency over the parent inhibitor
• High purity suitable for preclinical research
• DMSO soluble at ≥100 mg/mL for straightforward formulation
• Available in small research quantities for laboratory experiments

Catalog No. 50-002-88710