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AdipoGen Fostriecin (10 µg)
SDP

Supplier:  AdipoGen AGCN20057C010

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Chemical. CAS: 87860-39-7. Formula: C19H26O9PNa. MW: 452.4. Isolated from Streptomyces pulveraceous subsp. fostreus. Antibiotic. Anticancer compound. Antifungal. Catalytic inhibitor of topoisomerase II (IC50 = 40 µM). Potent protein phosphatase 2A (PP2A) (IC50 = 1.5 nM) and 4 (PP4) (IC50 = 3 nM) inhibitor. Weak protein phosphatase type 1 (PP1) inhibitor (IC50=131µM). No apparent inhibition on PP2B. Mitotic entry checkpoint inhibitor. Mediates cell cycle arrest at G2-M-phase. Ischemia protective. The PP2A binding site is different from that of okadaic acid

Catalog No. 50-205-3404


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