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AdipoGen anti-FOXP3 (mouse), mAb (MF333F) (50 µg)
Supplier: AdipoGen AG20A0025YC050
Monoclonal Antibody. Recognizes mouse FOXP3. Detects a band of ~46-49kDa by Western blot. Isotype: Rat IgG2akappa. Clone: MF333F. Applications: ELISA, ICC, IHC, WB. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. FOXP3 is involved in immune system responses. It functions as the master regulator in the development and function of regulatory T cells. FOX proteins belong to the forkhead/winged-helix family of transcriptional regulators and are presumed to exert control via similar DNA binding interactions during transcription. Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX); also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema.
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