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Abeomics Foxp3 Reporter Jurkat Line
Supplier: Abeomics 14144ACL
The FOXP3 Leeporter Luciferase Reporter cell line is a stably transfected Jurkat T cell line which expresses Renilla luciferase reporter gene under the transcriptional control of the Forkhead box P3 (FOXP3) promoter. As a member of the forkhead transcription factor family, FOXP3 is a key transcription factor that functions in the development and function of regulatory T cells. Functional activity of the cell line has been validated by phorbol 12-myristate 13-acetate (PMA) in the presence of ionomycin. Cell line application: (1) Monitor the FOXP3 induction activity, and (2) Screen for activators or inhibitors of FOXP3 indction. .
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