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Medchemexpress LLC FR054 | 35954-65-5 | 99.5% | 329.30 g/mol | C14H19NO8 | 10MG
Supplier: Medchemexpress LLC HY124909A10MG
FR054 is a small-molecule inhibitor of the hexosamine biosynthetic pathway enzyme PGM3 used in research to study glycosylation and cancer cell metabolism. It induces early proliferation arrest, endoplasmic reticulum stress, and ROS-dependent apoptotic cell death in breast cancer cells, reduces N- and O-glycosylation levels, and has shown tumor growth suppression in xenograft models.
- Inhibits PGM3, targeting hexosamine biosynthesis.
- Induces proliferation arrest and ROS-dependent apoptosis in cancer cells.
- Reduces N- and O-glycosylation levels in cell models.
- Shows tumor growth suppression in xenograft studies.
- Offered with high reported purity for research use.
- Available as solid forms and as a 10 mM solution in DMSO.
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