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ACROBiosystems Human Frizzled-7 Protein, Fc Tag, >95% Purity, 100 μg

Catalog No. 501658491
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Frizzled-7 (FZD7), also known as FzE3, is a member of the G-protein coupled receptor Fz/Smo family that functions as a receptor for Wnt proteins. It plays a critical role in the beta-catenin canonical signaling pathway by activating disheveled proteins, inhibiting GSK-3 kinase, and promoting nuclear accumulation of beta-catenin. This recombinant protein is expressed in human 293 cells (HEK293) and features a C-terminal human IgG1 Fc tag.

  • Expressed from human 293 cells (HEK293) with Gln 33 - Leu 185 amino acid sequence.
  • Purity >95% as determined by SDS-PAGE.
  • Calculated MW of 43.3 kDa, migrating at 50-60 kDa due to glycosylation.
  • Endotoxin level <1.0 EU per μg by LAL/rFC method.
  • Lyophilized from a solution in Tris, glycine, arginine, and NaCl (pH 7.5) with trehalose protectant.
  • Stable for 12 months at -20°C to -70°C in lyophilized state.

Catalog No. 50-165-8491 Supplier ACROBiosystems Supplier No. FZ7H5258100UG
May include imposed supplier surcharges.
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Frizzled-7 (FZD7), also known as FzE3, is a member of the G-protein coupled receptor Fz/Smo family that functions as a receptor for Wnt proteins. It plays a critical role in the beta-catenin canonical signaling pathway by activating disheveled proteins, inhibiting GSK-3 kinase, and promoting nuclear accumulation of beta-catenin. This recombinant protein is expressed in human 293 cells (HEK293) and features a C-terminal human IgG1 Fc tag.

  • Expressed from human 293 cells (HEK293) with Gln 33 - Leu 185 amino acid sequence.
  • Purity >95% as determined by SDS-PAGE.
  • Calculated MW of 43.3 kDa, migrating at 50-60 kDa due to glycosylation.
  • Endotoxin level <1.0 EU per μg by LAL/rFC method.
  • Lyophilized from a solution in Tris, glycine, arginine, and NaCl (pH 7.5) with trehalose protectant.
  • Stable for 12 months at -20°C to -70°C in lyophilized state.

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