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Cayman Chemical Frtlara thunberg Pemn 50mg

Supplier: Cayman Chemical 2996350 MG

A triterpenoid saponin inhibits NMDA-evoked currents in hippocampal neurons (IC50s 18 48 and 20 19 M at -50 and 50 mV respectively) and inhibits NMDA-induced neuronal cell death at 30 M increases the levels of 5-HT 5-HIAA and norepinephrine in the hippocampus and 5-HIAA and norepinephrine in the prefrontal cortex in mice at 30 and 100 mg/kg reduces the time spent immobile in the forced swim test in mice at 30 and 100 mg/kg increases the time spent in the target quadrant of the Morris water maze in mice at 100 mg/kg reduces infarct volume in an MCAO rat model of ischemia at 12 6 and 25 2 mg/kg induces relaxation of precontracted isolated rat thoracic aorta and renal mesenteric and left coronary arteries in a concentration-dependent manner
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