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Medchemexpress LLC FTI-277 hydrochloride | 180977-34-8 | 98.0% | 484.07 | 5 MG
SDP

Supplier:  Medchemexpress LLC 5MGHY15872A

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FTI-277 hydrochloride is an inhibitor of farnesyl transferase (FTase). It is a highly potent Ras CAAX peptidomimetic that antagonizes both H- and K-Ras oncogenic signaling and can inhibit hepatitis delta virus (HDV) infection.

  • Inhibits farnesyl transferase (FTase)
  • Antagonizes H- and K-Ras oncogenic signaling
  • Can inhibit hepatitis delta virus (HDV) infection
  • Significantly decreases survival of radioresistant cells expressing the 24-kDa isoform
  • Stimulates postmitotic cell death in HeLa 3A cells
  • Reduces G(2)/M-phase arrest in both cell types (HeLa 3A and HeLa PINA)
  • Inhibits migration and invasion in PC-3 cells
  • Prevents increased PTP-1B and PTEN protein expression in burned mice

Catalog No. 50-003-64660


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