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Cayman Chemical FTI276 trifluoroacetate salt
Supplier: Cayman Chemical 100116611 MG
A peptidomimetic inhibitor of FTase (IC50 = 500 pM); selective for FTase over GGTase I (IC50 = 50 nM); inhibits the growth of NIH3T3 cells expressing RasF at 20 µM; reduces tumor growth in a mouse xenograft model using Calu-1 cells that contain a K-Ras oncogenic mutation
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