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Eurofins Discoverx FTY720 Phosphate, 1 mg. (92-1104)
Supplier: Eurofins Discoverx 921104
FTY 720 phosphate, or Fingolimod, is a sphingosine analog and immunomodulating drug currently approved for multiple sclerosis treatment. It is derived from the fungal metabolite myriocin (ISP-1), and acts as a potent modulator for sphingosine-1 phosphate receptors, encouraging recruitment of lymphocytes into the CNS during an immune response. Acts as an agonist for S1P1 receptors S1PR1 (EDG1) and S1PR5 (EDG8) selectively, with no activity at S1PR2-4. Provided as 1 mg of dry powder. These highly purified, pre-validated control ligands have been used to qualify our InCELL Hunter, PathHunter and cAMP Hunter cell lines as well as our Assay Ready Kits. Ligands are conveniently supplied with a recommended reconstitution buffer. For detailed information and product-specific datasheet, visit www.discoverx.com/ligands.
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